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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P22695 |
| Other Accession | NP_003357.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Calculated MW | 48443 Da |
| Antigen Region | 235-264 aa |
| Gene ID | 7385 |
|---|---|
| Other Names | Cytochrome b-c1 complex subunit 2, mitochondrial, Complex III subunit 2, Core protein II, Ubiquinol-cytochrome-c reductase complex core protein 2, UQCRC2 |
| Target/Specificity | This UQCRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the Central region of human UQCRC2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UQCRC2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UQCRC2 |
|---|---|
| Function | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Hu, W.H., et al. J. Neurochem. 81(1):36-45(2002)
Duncan, A.M., et al. Genomics 18(2):455-456(1993)
Hosokawa, Y., et al. Biochem. Int. 20(4):731-737(1990)
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