|Application ||WB, E|
|Calculated MW||136377 Da|
|Antigen Region||150-178 aa|
|Other Names||Nidogen-1, NID-1, Entactin, NID1, NID|
|Target/Specificity||This NID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the N-terminal region of human NID1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NID1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions.|
|Cellular Location||Secreted, extracellular space, extracellular matrix, basement membrane|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.
Nischt, R., et al. J. Invest. Dermatol. 127(3):545-554(2007)
Ulazzi, L., et al. Mol. Cancer 6, 17 (2007) :
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Takagi, J., et al. Nature 424(6951):969-974(2003)
Piecha, D., et al. Biochem. J. 367 (PT 3), 715-721 (2002) :
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