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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Amyotrophic Lateral Sclerosis (ALS)   >   Mouse Map2k3 Antibody (Center)   

Mouse Map2k3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Map2k3 Antibody (Center) AP14441c
    Mouse Map2k3 Antibody (Center) (Cat. #AP14441c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).
  • WB - Mouse Map2k3 Antibody (Center) AP14441c
    Western blot analysis of Map2k3 (arrow) using rabbit polyclonal Mouse Map2k3 Antibody (Center) (Cat. #AP14441c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k3 gene.
  • WB - Mouse Map2k3 Antibody (Center) AP14441c
    Mouse Map2k3 Antibody (Center) (Cat. #AP14441c) western blot analysis in C6 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).
  • WB - Mouse Map2k3 Antibody (Center) AP14441c
    Mouse Map2k3 Antibody (Center) (Cat. #AP14441c) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O09110
Other Accession NP_032954.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39296 Da
Antigen Region 132-160 aa
Additional Information
Gene ID 26397
Other Names Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK/ERK kinase 3, MEK 3, Map2k3, Mkk3, Prkmk3
Target/Specificity This Mouse Map2k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of mouse Map2k3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Map2k3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Map2k3
Synonyms Mkk3, Prkmk3
Function Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
Research Areas
Citations (0)

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Background

Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38 (By similarity).

References

Yang, Z., et al. J. Immunol. 185(10):6205-6213(2010)
Remy, G., et al. Cell. Signal. 22(4):660-667(2010)
Behren, A., et al. Oncogene 29(10):1519-1530(2010)
Nagelin, M.H., et al. J. Biol. Chem. 284(45):31303-31314(2009)
Yoshizawa, T., et al. J. Immunol. 183(2):1360-1367(2009)

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$ 295.00
$ 99.00
Cat# AP14441c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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