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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SPAK (STK39) Antibody (C-term)   

SPAK (STK39) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - SPAK (STK39) Antibody (C-term) AP1448b
    STK39 Antibody (C-term) (Cat. #AP1448b) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STK39 antibody detected the STK39 protein (arrow).
  • IHC-P - SPAK (STK39) Antibody (C-term) AP1448b
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK39 antibody (C-term)(Cat.#AP1448b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UEW8
Other Accession O88506
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59474 Da
Antigen Region 386-415 aa
Additional Information
Gene ID 27347
Other Names STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK
Target/Specificity This SPAK (STK39) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPAK (STK39) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK39
Synonyms SPAK
Function May act as a mediator of stress-activated signals.
Cellular Location Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.
Tissue Location Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis
Research Areas
Citations (0)

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STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.


Dowd, B.F., et al., J. Biol. Chem. 278(30):27347-27353 (2003).
Johnston, A.M., et al., Oncogene 19(37):4290-4297 (2000).

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$ 295.00
$ 99.00
Cat# AP1448b
(40 western blots)
Availability: In Stock
Bulk Size
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