|Application ||WB, E|
|Other Accession||Q8VHR5, NP_065750.1|
|Calculated MW||65261 Da|
|Antigen Region||1-30 aa|
|Other Names||Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68, GATAD2B, KIAA1150|
|Target/Specificity||This GATAD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GATAD2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GATAD2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.|
|Cellular Location||Nucleus speckle. Note=Speckled nuclear localization requires both CR1 and CR2 regions|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GATAD2B has transcriptional repressor activity. Targets MBD3 to discrete loci in the nucleus.
Ichikawa, S., et al. J. Bone Miner. Res. 23(10):1680-1688(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Brackertz, M., et al. Nucleic Acids Res. 34(2):397-406(2006)
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