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SEC23IP Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEC23IP Antibody (C-term) AP14511b
    SEC23IP Antibody (C-term) (Cat. #AP14511b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SEC23IP antibody detected the SEC23IP protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6Y8
Other Accession NP_009121.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 111076 Da
Antigen Region 724-752 aa
Additional Information
Gene ID 11196
Other Names SEC23-interacting protein, p125, SEC23IP
Target/Specificity This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEC23IP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC23IP
Function Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
Cellular Location Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum
Tissue Location Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle
Research Areas
Citations ( 0 )


COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. [provided by RefSeq].


Ong, Y.S., et al. J. Cell Biol. 190(3):331-345(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Li, H., et al. J. Biol. Chem. 281(21):14748-14755(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Shimoi, W., et al. J. Biol. Chem. 280(11):10141-10148(2005)

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$ 295.00
$ 99.00
Cat# AP14511b
(40 western blots)
Availability: In Stock
Bulk Size
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