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ATP2B4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ATP2B4 Antibody (C-term) AP14531B
    ATP2B4 Antibody (C-term) (Cat. #AP14531b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ATP2B4 antibody detected the ATP2B4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23634
Other Accession NP_001675.3, NP_001001396.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 137920 Da
Antigen Region 1174-1202 aa
Additional Information
Gene ID 493
Other Names Plasma membrane calcium-transporting ATPase 4, PMCA4, Matrix-remodeling-associated protein 1, Plasma membrane calcium ATPase isoform 4, Plasma membrane calcium pump isoform 4, ATP2B4, ATP2B2, MXRA1
Target/Specificity This ATP2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1174-1202 amino acids from the C-terminal region of human ATP2B4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATP2B4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP2B4
Synonyms ATP2B2, MXRA1
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].


Holton, M., et al. Cardiovasc. Res. 87(3):440-448(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Juranic, N., et al. J. Biol. Chem. 285(6):4015-4024(2010)
Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
Aung, C.S., et al. Carcinogenesis 30(11):1962-1969(2009)

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$ 295.00
$ 99.00
Cat# AP14531B
(40 western blots)
Availability: In Stock
Bulk Size
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