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MEOX1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MEOX1 Antibody (Center) AP14566C
    Anti-MEOX1 Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - MEOX1 Antibody (Center) AP14566C
    MEOX1 Antibody (Center) (Cat. #AP14566c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MEOX1 antibody detected the MEOX1 protein (arrow).
  • WB - MEOX1 Antibody (Center) AP14566C
    Western blot analysis of MEOX1 (arrow) using rabbit polyclonal MEOX1 Antibody (Center) (Cat. #AP14566c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MEOX1 gene.
  • IHC-P - MEOX1 Antibody (Center) AP14566C
    MEOX1 Antibody (Center) (AP14566c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MEOX1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50221
Other Accession NP_004518.1, NP_001035091.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27997 Da
Antigen Region 136-165 aa
Additional Information
Gene ID 4222
Other Names Homeobox protein MOX-1, Mesenchyme homeobox 1, MEOX1, MOX1
Target/Specificity This MEOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the Central region of human MEOX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMEOX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEOX1
Synonyms MOX1
Function Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Cellular Location Nucleus {ECO:0000250|UniProtKB:P32442}. Cytoplasm {ECO:0000250|UniProtKB:P32442}. Note=Localizes predominantly in the nucleus. {ECO:0000250|UniProtKB:P32442}
Research Areas
Citations (0)

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This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.


Vatanavicharn, N., et al. Am. J. Med. Genet. A 143A (19), 2292-2302 (2007) :
Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Gianakopoulos, P.J., et al. J. Biol. Chem. 280(22):21022-21028(2005)
Petropoulos, H., et al. J. Biol. Chem. 279(23):23874-23881(2004)
Stamataki, D., et al. FEBS Lett. 499(3):274-278(2001)

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$ 295.00
$ 99.00
Cat# AP14566C
(40 western blots)
Availability: In Stock
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