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Mouse Epha1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Epha1 Antibody (Center) AP14618C
    Mouse Epha1 Antibody (Center) (Cat. #AP14618c) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Epha1 antibody detected the Epha1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q60750
Other Accession NP_076069.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 108578 Da
Antigen Region 339-366 aa
Additional Information
Gene ID 13835
Other Names Ephrin type-A receptor 1, mEpha1, Embryonic stem cell kinase, Tyrosine-protein kinase receptor ESK, Epha1, Esk
Target/Specificity This Mouse Epha1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339-366 amino acids from the Central region of mouse Epha1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Epha1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Epha1
Synonyms Esk
Function Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Preferentially expressed in epithelial cells including skin, kidney, liver and thymus
Research Areas
Citations (0)

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Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1.


Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010)
Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009)
North, H.A., et al. Development 136(14):2467-2476(2009)
Abdul-Aziz, N.M., et al. Int. J. Dev. Biol. 53(4):559-568(2009)
Duffy, S.L., et al. Genesis 46(10):553-561(2008)

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$ 295.00
$ 99.00
Cat# AP14618C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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