|Application ||WB, E|
|Calculated MW||25919 Da|
|Antigen Region||51-79 aa|
|Other Names||Ribosyldihydronicotinamide dehydrogenase [quinone], NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2, NQO2, NMOR2|
|Target/Specificity||This NQO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human NQO2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NQO2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
NQO2 (EC 22.214.171.124) is a flavoprotein that catalyzes the 2-electron reduction of various quinones, redox dyes, and the vitamin K menadione. NQO2 predominantly uses dihydronicotinamide riboside (NRH) as the electron donor (summary by Wu et al., 1997 [PubMed 9367528]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ji, L.D., et al. J. Pineal Res. 48(2):133-141(2010)
Yu, K.D., et al. Breast Cancer Res. Treat. 118(3):647-649(2009)
Choi, J.Y., et al. Clin. Cancer Res. 15(16):5258-5266(2009)
Yu, K.D., et al. Hum. Mol. Genet. 18(13):2502-2517(2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.