|Application ||WB, E|
|Calculated MW||18937 Da|
|Antigen Region||13-41 aa|
|Other Names||Olfactory marker protein, Olfactory neuronal-specific protein, OMP|
|Target/Specificity||This OMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human OMP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OMP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a modulator of the olfactory signal- transduction cascade.|
|Tissue Location||Uniquely associated with mature olfactory receptor neurons|
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Provided below are standard protocols that you may find useful for product applications.
Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Behrens, M., et al. J. Neurochem. 86(5):1289-1296(2003)
Baldisseri, D.M., et al. J. Mol. Biol. 319(3):823-837(2002)
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