|Application ||WB, IHC-P, E|
|Calculated MW||63153 Da|
|Antigen Region||431-460 aa|
|Other Names||Transmembrane protease serine 13, 3421-, Membrane-type mosaic serine protease, Mosaic serine protease, TMPRSS13, MSP, TMPRSS11|
|Target/Specificity||This TMPRSS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-460 amino acids from the C-terminal region of human TMPRSS13.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMPRSS13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Isoform 1 and isoform 3 are predominantly expressed in lung, placenta, pancreas, and prostate. Isoform 3 is weakly expressed in testis and peripheral blood lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
TMPRSS13 is a cell membrane serine protease. It is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase 1, 2 and 3. TMPRSS13 has a domain structure of an aminoterminal cytoplasmic domain, which is much longer than the other TMPRSS family members, followed by a transmembrane domain, an SRCR domain (Scavenger receptor cysteine rich), an LDL receptor like domain, another SRCR domain, followed by the trypsin like serine protease domain. The cytoplasmic domain contains a number of tandem repeat elements, the function of which is not clear, but which may play a regulatory role.
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