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IL17D Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - IL17D Antibody (C-term) AP14679B
    IL17D Antibody (C-term) (Cat. #AP14679b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IL17D antibody detected the IL17D protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8TAD2
Other Accession NP_612141.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21893 Da
Antigen Region 155-183 aa
Additional Information
Gene ID 53342
Other Names Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27
Target/Specificity This IL17D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the C-terminal region of human IL17D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL17D Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17D
Function Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Cellular Location Secreted.
Tissue Location Expressed preferentially in adipose, skeletal muscle and CNS.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Fakruddin, J.M., et al. Blood 109(5):1841-1849(2007)
Larousserie, F., et al. J. Immunol. 176(10):5890-5897(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Starnes, T., et al. J. Immunol. 169(2):642-646(2002)

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$ 365.00
$ 140.00
Cat# AP14679B
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