|Application ||WB, E|
|Other Accession||P33671, Q64519, NP_055469.3|
|Calculated MW||45497 Da|
|Antigen Region||413-442 aa|
|Other Names||Syndecan-3, SYND3, SDC3, KIAA0468|
|Target/Specificity||This SDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the C-terminal region of human SDC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SDC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in the nervous system, the adrenal gland, and the spleen.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.
Schuring, A.N., et al. J. Mol. Med. 87(12):1241-1250(2009)
Marzioni, D., et al. Int J Immunopathol Pharmacol 22(3):627-638(2009)
Yao, J., et al. Dig. Dis. Sci. 54(4):895-901(2009)
Landgraf, P., et al. J. Biol. Chem. 283(36):25036-25045(2008)
Dews, I.C., et al. Proc. Natl. Acad. Sci. U.S.A. 104(52):20782-20787(2007)
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