|Application ||WB, IHC-P, E|
|Other Accession||NP_001171277.1, NP_038747.2|
|Calculated MW||186487 Da|
|Antigen Region||1477-1504 aa|
|Other Names||Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, mGCN2, Eif2ak4, Gcn2, Kiaa1338|
|Target/Specificity||This Mouse Eif2ak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1477-1504 amino acids from the C-terminal region of mouse Eif2ak4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Eif2ak4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.|
|Tissue Location||Expressed in liver (at protein level). Widely expressed, with the highest levels in the liver and the brain Isoform 4 is expressed in brain followed by testis and liver and isoform 3 is expressed only in brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Eif2ak4 can phosphorylate the alpha subunit of EIF2 and may mediate translational control.
Bunpo, P., et al. J. Nutr. 140(11):2020-2027(2010)
Ye, J., et al. EMBO J. 29(12):2082-2096(2010)
Liu, Y., et al. Neoplasia 12(1):61-68(2010)
Jasperson, L.K., et al. Blood 114(24):5062-5070(2009)
Bunpo, P., et al. J. Biol. Chem. 284(47):32742-32749(2009)
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