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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLA2G5 Antibody (C-term)   

PLA2G5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PLA2G5 Antibody (C-term) AP14763b
    PLA2G5 Antibody (C-term) (Cat. #AP14763b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PLA2G5 antibody detected the PLA2G5 protein (arrow).
  • IHC-P - PLA2G5 Antibody (C-term) AP14763b
    PLA2G5 Antibody (C-term) (AP14763b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLA2G5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P39877
Other Accession NP_000920.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 15674 Da
Antigen Region 103-132 aa
Additional Information
Gene ID 5322
Other Names Calcium-dependent phospholipase A2, Group V phospholipase A2, PLA2-10, Phosphatidylcholine 2-acylhydrolase 5, PLA2G5
Target/Specificity This PLA2G5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human PLA2G5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLA2G5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G5
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
Cellular Location Secreted.
Tissue Location Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level).
Research Areas
Citations (0)

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This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq].


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wootton, P.T., et al. Hum. Mol. Genet. 16(12):1437-1444(2007)
de Beer, F.C., et al. Arterioscler. Thromb. Vasc. Biol. 26(7):1421-1422(2006)

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Cat# AP14763b
(40 western blots)
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