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SEPT5 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPT5 Antibody (N-term) AP14767a
    Western blot analysis of lysate from human brain tissue lysate, using SEPT5 Antibody (N-term)(Cat. #AP14767a). AP14767a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - SEPT5 Antibody (N-term) AP14767a
    SEPT5 Antibody (N-term) (AP14767a)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEPT5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99719
Other Accession Q9JJM9, Q9Z2Q6, NP_002679.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42777 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 5413
Other Names Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1, SEPT5, PNUTL1
Target/Specificity This SEPT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEPT5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPT5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT5
Synonyms PNUTL1
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules
Tissue Location Expressed at high levels in the CNS, as well as in heart and platelets (at protein level)
Research Areas
Citations (0)

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This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq].


Jung, A.E., et al. Mol. Ther. 16(6):1048-1055(2008)
Amin, N.D., et al. J. Neurosci. 28(14):3631-3643(2008)
Xin, X., et al. J. Histochem. Cytochem. 55(11):1089-1094(2007)
Blaser, S., et al. J. Pathol. 210(1):103-110(2006)
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)

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$ 295.00
$ 99.00
Cat# AP14767a
(40 western blots)
Availability: In Stock
Bulk Size
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