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HSPBP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HSPBP1 Antibody (N-term) AP14772A
    HSPBP1 Antibody (N-term) (Cat. #AP14772a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HSPBP1 antibody detected the HSPBP1 protein (arrow).
  • IHC-P - HSPBP1 Antibody (N-term) AP14772A
    HSPBP1 Antibody (N-term) (AP14772a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSPBP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZL4
Other Accession Q6IMX7, Q99P31, Q4R588, NP_036399.3, NP_001123578.1
Reactivity Human
Predicted Monkey, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39474 Da
Antigen Region 69-97 aa
Additional Information
Gene ID 23640
Other Names Hsp70-binding protein 1, HspBP1, Heat shock protein-binding protein 1, Hsp70-binding protein 2, HspBP2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPBP1, HSPBP
Target/Specificity This HSPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the N-terminal region of human HSPBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHSPBP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HSPBP
Function Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.


Graner, M.W., et al. Cancer Sci. 100(10):1870-1879(2009)
Evdonin, A., et al. Biol. Cell 101(6):351-360(2009)
Souza, A.P., et al. Cell Stress Chaperones 14(3):301-310(2009)
Howarth, J.L., et al. J. Neurochem. 108(4):945-951(2009)
Snyers, L., et al. Biochem. Biophys. Res. Commun. 368(3):767-771(2008)

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Cat# AP14772A
(40 western blots)
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