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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Insrr Antibody (C-term)   

Mouse Insrr Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Insrr Antibody (C-term) AP14784B
    Mouse Insrr Antibody (C-term) (Cat. #AP14784b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Insrr antibody detected the Insrr protein (arrow).
  • WB - Mouse Insrr Antibody (C-term) AP14784B
    Mouse Insrr Antibody (C-term) (Cat. #AP14784b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Insrr antibody detected the Insrr protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9WTL4
Other Accession Q64716, NP_035962.2
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 144875 Da
Antigen Region 1228-1255 aa
Additional Information
Gene ID 23920
Other Names Insulin receptor-related protein, IRR, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, Insrr, Irr
Target/Specificity This Mouse Insrr antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1228-1255 amino acids from the C-terminal region of mouse Insrr.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Insrr Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Insrr
Synonyms Irr
Function Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in the islets as well as in pancreatic beta-cells.
Research Areas
Citations (0)

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This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.


Hanke, S., et al. Mol. Cell Proteomics 8(3):519-534(2009)
Hoffman, B.G., et al. Genome Biol. 9 (6), R99 (2008) :
Nef, S., et al. Nature 426(6964):291-295(2003)
Kitamura, T., et al. Mol. Cell. Biol. 21(16):5624-5630(2001)
Tsuji, T., et al. Exp. Anim. 50(4):359-360(2001)

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$ 295.00
$ 99.00
Cat# AP14784B
(40 western blots)
Availability: In Stock
Bulk Size
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