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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD106 Antibody (Center)   

CD106 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CD106 Antibody (Center) AP14788c
    CD106 Antibody (Center) (Cat. #AP14788c) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CD106 antibody detected the CD106 protein (arrow).
  • WB - CD106 Antibody (Center) AP14788c
    CD106 Antibody (Center) (Cat. #AP14788c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CD106 antibody detected the CD106 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19320
Other Accession NP_001069.1, NP_542413.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 81276 Da
Antigen Region 295-322 aa
Additional Information
Gene ID 7412
Other Names Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM
Target/Specificity This CD106 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human CD106.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD106 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VCAM1
Synonyms L1CAM
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue
Research Areas
Citations (0)

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This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Beckers, M.M., et al. Eur. J. Intern. Med. 21(4):289-292(2010)
Jin, C., et al. Coron. Artery Dis. 21(5):273-277(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Wang, Y., et al. Diabet. Med. 27(4):376-383(2010)

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Cat# AP14788c
(40 western blots)
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