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CD9 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1482a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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CD9 Antibody (N-term) - Product info | |
| Application | WB, FC
|
| Primary Accession | P21926 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 25416 Da |
CD9 Antibody (N-term) - Additional info | |
| Gene ID 928 | |
| Other Names CD9; MIC3; TSPAN29; CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; Tetraspanin-29; p24; CD_antigen=CD9 | |
| Target/Specificity This CD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29~58 amino acids from the N-terminal region of human CD9. | |
| Dilution WB~~1:50~100WB~~1:1000 FC~~1:10~50 | |
| Format Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CD9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
CD9 Antibody (N-term) - Protein Information | |
| Name CD9 | |
| Synonyms MIC3, TSPAN29 | |
| Function Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion | |
| Cellular Location Membrane; Multi-pass membrane protein. | |
| Tissue Location Expressed by a variety of hematopoietic and epithelial cells | |
CD9 Antibody (N-term) - Related products
AP1482a: CD9 Antibody (N-term)
AP1482d: CD9 Antibody (Center)
LY10754a: CD9 Over-expression Lysate
BP1482a: CD9 Antibody (N-term) Blocking Peptide
CD9 Antibody (N-term) - Application data
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Western blot analysis of CD9 Antibody (N-term) (Cat.#AP1482a) in Jurkat cell line lysates (35ug/lane). CD9 (arrow) was detected using the purified Pab (1:60 dilution).
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Western blot analysis of CD9(arrow) using rabbit polyclonal CD9 Antibody (N-term) (Cat.#AP1482a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CD9 gene (Lane 2) (Origene Technologies).
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Flow cytometric analysis of jurkat cells using CD9 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
CD9 Antibody (N-term) - Research Areas
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BACKGROUND
CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance.
REFERENCES
Ovalle,S., Int. J. Cancer 121 (10), 2140-2152 (2007) Kovalenko,O.V., Mol. Cell Proteomics 6 (11), 1855-1867 (2007) Abache,T., J. Cell. Biochem. 102 (3), 650-664 (2007) Horejsi,V., FEBS Lett. 288 (1-2), 1-4 (1991)
