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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Mouse Frk Antibody (C-term)   

Mouse Frk Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Frk Antibody (C-term) AP14842b
    Mouse Frk Antibody (C-term) (Cat. #AP14842b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Frk antibody detected the Frk protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q922K9
Other Accession Q62662, NP_034367.2, NP_001153016.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58844 Da
Antigen Region 464-491 aa
Additional Information
Gene ID 14302
Other Names Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
Target/Specificity This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Frk Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Frk
Synonyms Bsk, Iyk
Function Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Tissue Location Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung
Research Areas
Citations (0)

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Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).


Akerblom, B., et al. Mol. Cell. Endocrinol. 270 (1-2), 73-78 (2007) :
Nishimura, M., et al. DNA Res. 11(5):315-323(2004)
Sharov, A.A., et al. PLoS Biol. 1 (3), E74 (2003) :
Cowen, M.S., et al. Alcohol. Clin. Exp. Res. 27(8):1213-1219(2003)
Serfas, M.S., et al. Oncol. Res. 13 (6-10), 409-419 (2003) :

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$ 295.00
$ 99.00
Cat# AP14842b
(40 western blots)
Availability: In Stock
Bulk Size
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