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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   NTN3 Antibody (C-term)   

NTN3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NTN3 Antibody (C-term) AP14887b
    NTN3 Antibody (C-term) (Cat. #AP14887b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NTN3 antibody detected the NTN3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O00634
Other Accession NP_006172.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 431-459 aa
Additional Information
Other Names Netrin-3, Netrin-2-like protein, NTN3, NTN2L
Target/Specificity This NTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-459 amino acids from the C-terminal region of human NTN3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNTN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTN3
Synonyms NTN2L
Function Netrins control guidance of CNS commissural axons and peripheral motor axons.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Spinal cord.. EMBL; U86759; AAC51247.1; -; mRNA EMBL; U86758; AAC51246.1; -; Genomic_DNA CCDS; CCDS10469.1; - RefSeq; NP_006172.1; NM_006181.2 UniGene; Hs.158336; - ProteinModelPortal; O00634; - SMR; O00634; - IntAct; O00634; 1 STRING; 9606.ENSP00000293973; - iPTMnet; O00634; - PhosphoSitePlus; O00634; - BioMuta; NTN3; - PaxDb; O00634; - PeptideAtlas; O00634; - PRIDE; O00634; - ProteomicsDB; 48004; - Ensembl; ENST00000293973; ENSP00000293973; ENSG00000162068 GeneID; 4917; - KEGG; hsa:4917; - UCSC; uc002cqj.3; human CTD; 4917; - EuPathDB; HostDB:ENSG00000162068.1; - GeneCards; NTN3; - HGNC; HGNC:8030; NTN3 HPA; HPA050817; - MIM; 602349; gene neXtProt; NX_O00634; - OpenTargets; ENSG00000162068; - PharmGKB; PA164724231; - eggNOG; KOG3512; Eukaryota eggNOG; ENOG410XS7U; LUCA GeneTree; ENSGT00890000139348; - HOGENOM; HOG000286017; - HOVERGEN; HBG006464; - InParanoid; O00634; - KO; K06844; - OMA; LRFCSAP; - OrthoDB; EOG091G005L; - PhylomeDB; O00634; - TreeFam; TF352481; - Reactome; R-HSA-375170; CDO in myogenesis GenomeRNAi; 4917; - PRO; PR:O00634; - Proteomes; UP000005640; Chromosome 16 Bgee; ENSG00000162068; - CleanEx; HS_NTN3; - Genevisible; O00634; HS GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl GO; GO:0007411; P:axon guidance; NAS:UniProtKB Gene3D; 2.60.120.1490; -; 1 InterPro; IPR002049; Laminin_EGF InterPro; IPR008211; Laminin_N InterPro; IPR038684; Laminin_N_sf InterPro; IPR001134; Netrin_domain InterPro; IPR018933; Netrin_module_non-TIMP InterPro; IPR008993; TIMP-like_OB-fold Pfam; PF00053; Laminin_EGF; 3 Pfam; PF00055; Laminin_N; 1 Pfam; PF01759; NTR; 1 SMART; SM00643; C345C; 1 SMART; SM00180; EGF_Lam; 3 SMART; SM00136; LamNT; 1 SUPFAM; SSF50242; SSF50242; 1 PROSITE; PS00022; EGF_1; 2 PROSITE; PS01248; EGF_LAM_1; 3 PROSITE; PS50027; EGF_LAM_2; 3 PROSITE; PS51117; LAMININ_NTER; 1 PROSITE; PS50189; NTR; 1 1: Evidence at protein level; Complete proteome; Disulfide bond; Extracellular matrix; Glycoprotein; Laminin EGF-like domain; Polymorphism; Reference proteome; Repeat; Secreted; Signal SIGNAL 1 27 CHAIN 28 580 Netrin-3 /FTId=PRO_0000017085 DOMAIN 36 254 Laminin N-terminal. {ECO:0000255|PROSITE- ProRule:PRU00466} DOMAIN 255 308 Laminin EGF-like 1. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 311 371 Laminin EGF-like 2. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 374 421 Laminin EGF-like 3. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 441 577 NTR. {ECO:0000255|PROSITE- ProRule:PRU00295} MOTIF 500 502 Cell attachment site; atypical CARBOHYD 104 104 N-linked (GlcNAc...) asparagine CARBOHYD 387 387 N-linked (GlcNAc...) asparagine DISULFID 92 125 DISULFID 255 264 DISULFID 257 274 DISULFID 276 285 DISULFID 288 308 DISULFID 311 320 DISULFID 313 338 DISULFID 341 350 DISULFID 353 371 DISULFID 374 386 DISULFID 376 393 DISULFID 395 404 DISULFID 407 421 DISULFID 441 514 DISULFID 460 577 VARIANT 425 425 P -> S (in dbSNP:rs34818219) /FTId=VAR_050086 SEQUENCE 580 AA; 61466 MW; 15F99643E74C644C CRC64; MPGWPWGLLL TAGTLFAALS PGPPAPADPC HDEGGAPRGC VPGLVNAALG REVLASSTCG RPATRACDAS DPRRAHSPAL LTSPGGTASP LCWRSESLPR APLNVTLTVP LGKAFELVFV SLRFCSAPPA SVALLKSQDH GRSWAPLGFF SSHCDLDYGR LPAPANGPAG PGPEALCFPA PLAQPDGSGL LAFSMQDSSP PGLDLDSSPV LQDWVTATDV RVVLTRPSTA GDPRDMEAVV PYSYAATDLQ VGGRCKCNGH ASRCLLDTQG HLICDCRHGT EGPDCGRCKP FYCDRPWQRA TARESHACLA CSCNGHARRC RFNMELYRLS GRRSGGVCLN CRHNTAGRHC HYCREGFYRD PGRALSDRRA CRACDCHPVG AAGKTCNQTT GQCPCKDGVT GLTCNRCAPG FQQSRSPVAP CVKTPIPGPT EDSSPVQPQD CDSHCKPARG SYRISLKKFC KKDYAVQVAV GARGEARGAW TRFPVAVLAV FRSGEERARR GSSALWVPAG DAACGCPRLL PGRRYLLLGG GPGAAAGGAG GRGPGLIAAR GSLVLPWRDA WTRRLRRLQR RERRGRCSAA
Research Areas
Citations (0)

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Background

Netrins control guidance of CNS commissural axons and peripheral motor axons (By similarity).

References

Latil, A., et al. Int. J. Cancer 103(3):306-315(2003)
Laszlo, T., et al. Leuk. Res. 24(1):27-31(2000)
Hamblin, T.J., et al. Blood 94(6):1848-1854(1999)
Wang, H., et al. J. Neurosci. 19(12):4938-4947(1999)
de Wildt, R.M., et al. J. Mol. Biol. 285(3):895-901(1999)

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$ 295.00
$ 99.00
Cat# AP14887b
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(40 western blots)
Availability: In Stock
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