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TADA2L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TADA2L Antibody (Center) AP14912C
    TADA2L Antibody (Center) (Cat. #AP14912c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TADA2L antibody detected the TADA2L protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75478
Other Accession Q6AYE3, Q8CHV6, Q3SZP8, NP_597683.2, NP_001479.3
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51506 Da
Antigen Region 202-230 aa
Additional Information
Gene ID 6871
Other Names Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L
Target/Specificity This TADA2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human TADA2L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTADA2L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TADA2L
Function Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.
Cellular Location Nucleus. Chromosome.
Tissue Location Expressed in all tissues, but most abundantly in testis
Citations (0)

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Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.


Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Yang, M., et al. Cancer Biol. Ther. 7(1):120-128(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Qian, C., et al. Nat. Struct. Mol. Biol. 12(12):1078-1085(2005)
Barlev, N.A., et al. Mol. Cell. Biol. 23(19):6944-6957(2003)

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$ 295.00
$ 99.00
Cat# AP14912C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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