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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Actin (ACTB/ACTC) Antibody (Center)   

Actin (ACTB/ACTC) Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Actin (ACTB/ACTC) Antibody (Center) AP1491c
    Western blot analysis of ACTB/ACTC Antibody (Center) in HL60 cell line lysates (35ug/lane). Target protein (arrow) was detected using the purified Pab.
  • WB - Actin (ACTB/ACTC) Antibody (Center) AP1491c
    Western blot analysis of ACTB/ACTC (arrow) using rabbit polyclonal ACTB/ACTC Antibody (Center) (Cat.#AP1491a).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACTB/ACTC gene (Lane 2) (Origene Technologies).
  • IHC-P - Actin (ACTB/ACTC) Antibody (Center) AP1491c
    Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ACTB/ACTC antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P68032
Other Accession P60010, P68136, P68135, P68137, P68134, P68133, P68139, P68138, P63269, P63268, P63267, P63270, Q5E9B5, A2BDB0, P63259, P63260, P63261, Q5ZMQ2, P63258, P04751, P68035, P68033, P68034, Q3ZC07, O93400, P60711, P29751, Q6QAQ1, P60710, Q4R561, P60709, P48975
Reactivity Human
Predicted C.Elegans, Drosophila, Xenopus, Chicken, Bovine, Mouse, Rabbit, Rat, Zebrafish, Hamster, Horse, Monkey, Pig, Sheep, Yeast
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42019 Da
Antigen Region 189-218 aa
Additional Information
Gene ID 70
Other Names Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC
Target/Specificity This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the Central region of human Actin (ACTB/ACTC).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsActin (ACTB/ACTC) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACTC1
Synonyms ACTC
Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations (0)

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Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).


Villebeck,L., Biochemistry 46 (44), 12639-12647 (2007)
Avizienyte,E., Exp. Cell Res. 313 (15), 3175-3188 (2007)
Bouldin,A.A., Muscle Nerve 35 (2), 254-258 (2007)

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Cat# AP1491c
(40 western blots)
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