|Application ||WB, E|
|Other Accession||Q9D9M2, A5D9H7, Q5M981, Q52KZ6, NP_872294.2|
|Calculated MW||42858 Da|
|Antigen Region||222-251 aa|
|Other Names||Ubiquitin carboxyl-terminal hydrolase 12, Deubiquitinating enzyme 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12, USP12, UBH1, USP12L1|
|Target/Specificity||This USP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the Central region of human USP12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||USP12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.|
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Provided below are standard protocols that you may find useful for product applications.
USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Kee, Y., et al. J. Biol. Chem. 285(15):11252-11257(2010)
Asano, K., et al. Nat. Genet. 41(12):1325-1329(2009)
Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Puente, X.S., et al. Nat. Rev. Genet. 4(7):544-558(2003)
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