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Mouse Dclk1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Dclk1 Antibody (N-term) AP14964a
    Mouse Dclk1 Antibody (N-term) (Cat. #AP14964a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dclk1 antibody detected the Dclk1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9JLM8
Other Accession NP_064362.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 84153 Da
Antigen Region 153-181 aa
Additional Information
Gene ID 13175
Other Names Serine/threonine-protein kinase DCLK1, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, Dclk1, Dcamkl1, Dclk
Target/Specificity This Mouse Dclk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the N-terminal region of mouse Dclk1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Dclk1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dclk1
Synonyms Dcamkl1, Dclk
Function Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system (By similarity).
Research Areas
Citations (0)

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This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, but the biological validity of some variants has not been determined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.


Dijkmans, T.F., et al. Cent Nerv Syst Agents Med Chem 10(1):32-46(2010) Munger, S.C., et al. Genes Dev. 23(21):2521-2536(2009) Tsang, W.H., et al. Genomics 94(3):177-187(2009) Boekhoorn, K., et al. J. Comp. Neurol. 507(4):1639-1652(2008) Tuy, F.P., et al. Dev. Neurosci. 30 (1-3), 171-186 (2008) :

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Cat# AP14964a
(40 western blots)
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