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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Connexin 37 Antibody (C-term)   

Connexin 37 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Connexin 37 Antibody (C-term) AP1544b
    GJA4 Antibody (K317).Connexin (Cat. #AP1544b) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the GJA4 antibody detected the GJA4 protein (arrow).
  • IHC-P - Connexin 37 Antibody (C-term) AP1544b
    Connexin 37 Antibody (GJA4) (C-term) (Cat. #AP1544b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Connexin 37 Antibody (GJA4) (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35212
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37414 Da
Antigen Region 303-333 aa
Additional Information
Gene ID 2701
Other Names Gap junction alpha-4 protein, Connexin-37, Cx37, GJA4
Target/Specificity This Connexin 37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human Connexin 37.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsConnexin 37 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJA4
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Tissue Location Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium
Research Areas
Citations (0)

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Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Saito, T., et al., Int. J. Cancer 86(1):67-70 (2000).
Boerma, M., et al., J. Intern. Med. 246(2):211-218 (1999).
Krutovskikh, V., et al., Carcinogenesis 17(8):1761-1763 (1996).
Reed, K.E., et al., J. Clin. Invest. 91(3):997-1004 (1993).

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$ 295.00
$ 99.00
Cat# AP1544b
(40 western blots)
Availability: In Stock
Bulk Size
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