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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Cdk20 Antibody (Center)   

Mouse Cdk20 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Cdk20 Antibody (Center) AP16072c
    Mouse Cdk20 Antibody (Center) (Cat. #AP16072c) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Cdk20 antibody detected the Cdk20 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9JHU3
Other Accession Q4KM34, NP_444410.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38379 Da
Antigen Region 185-212 aa
Additional Information
Gene ID 105278
Other Names Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, CDK-related protein kinase PNQLARE, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, Cdk20, Ccrk, Cdch
Target/Specificity This Mouse Cdk20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the Central region of mouse Cdk20.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Cdk20 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cdk20
Synonyms Ccrk, Cdch
Function Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.
Cellular Location Nucleus. Cytoplasm. Cell projection, cilium
Research Areas
Citations (0)

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Background

Cdk20 is involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.

References

Qiu, H., et al. J. Biol. Chem. 283(32):22157-22165(2008)
Wohlbold, L., et al. Cell Cycle 5(5):546-554(2006)

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$ 295.00
$ 99.00
Cat# AP16072c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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