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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AGFG1 Antibody (N-term)   

AGFG1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AGFG1 Antibody (N-term) AP16184a
    AGFG1 Antibody (N-term) (Cat. #AP16184a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the AGFG1 antibody detected the AGFG1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P52594
Other Accession Q4KLH5, Q8K2K6, Q2TA45, NP_004495.2, NP_001128661.1, NP_001128660.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58260 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 3267
Other Names Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein, AGFG1, HRB, RAB, RIP
Target/Specificity This AGFG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AGFG1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGFG1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGFG1
Synonyms HRB, RAB, RIP
Function Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Cellular Location Nucleus. Cytoplasmic vesicle.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.


Bowes, J.D., et al. Pharmacogenet. Genomics 19(4):319-323(2009)
Chaineau, M., et al. J. Biol. Chem. 283(49):34365-34373(2008)
Pryor, P.R., et al. Cell 134(5):817-827(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 295.00
$ 99.00
Cat# AP16184a
(40 western blots)
Availability: In Stock
Bulk Size
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