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AGFG1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16184a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16184a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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AGFG1 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P52594 |
| Other Accession | Q4KLH5, Q8K2K6, Q2TA45, NP_004495.2, NP_001128661.1, NP_001128660.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 58260 Da |
AGFG1 Antibody (N-term) - Additional info | |
| Gene ID 3267 | |
| Other Names AGFG1; HRB; RAB; RIP; Arf-GAP domain and FG repeat-containing protein 1; HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein | |
| Target/Specificity This AGFG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AGFG1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AGFG1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AGFG1 Antibody (N-term) - Protein Information | |
| Name AGFG1 | |
| Synonyms HRB, RAB, RIP | |
| Function Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication | |
| Cellular Location Nucleus. Cytoplasmic vesicle. | |
| Tissue Location Ubiquitously expressed. | |
AGFG1 Antibody (N-term) - Related products
AP16184a: AGFG1 Antibody (N-term)
AGFG1 Antibody (N-term) - Application data
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AGFG1 Antibody (N-term) (Cat. #AP16184a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the AGFG1 antibody detected the AGFG1 protein (arrow).
AGFG1 Antibody (N-term) - Research Areas
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BACKGROUND
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Bowes, J.D., et al. Pharmacogenet. Genomics 19(4):319-323(2009) Chaineau, M., et al. J. Biol. Chem. 283(49):34365-34373(2008) Pryor, P.R., et al. Cell 134(5):817-827(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Olsen, J.V., et al. Cell 127(3):635-648(2006)
