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CPT1C Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CPT1C Antibody (C-term) AP16195b
    CPT1C Antibody (C-term) (Cat. #AP16195b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CPT1C antibody detected the CPT1C protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TCG5
Other Accession NP_001129524.1, NP_689572.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90989 Da
Antigen Region 596-625 aa
Additional Information
Gene ID 126129
Other Names Carnitine O-palmitoyltransferase 1, brain isoform, CPT1-B, CPT IC, Carnitine O-palmitoyltransferase I, brain isoform, CPTI-B, Carnitine palmitoyltransferase 1C, CPT1C, CATL1
Target/Specificity This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-625 amino acids from the C-terminal region of human CPT1C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCPT1C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1C
Synonyms CATL1
Function May play a role in lipid metabolic process.
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse {ECO:0000250|UniProtKB:Q8BGD5}. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BGD5}. Note=Localized in the soma and dendritic and axonal projections.
Tissue Location Expressed predominantly in brain and testis. Expressed in motor neurons.
Research Areas
Citations (0)

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The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Roomets, E., et al. Invest. Ophthalmol. Vis. Sci. 49(4):1660-1664(2008)
Sierra, A.Y., et al. J. Biol. Chem. 283(11):6878-6885(2008)
Price, N., et al. Genomics 80(4):433-442(2002)

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$ 295.00
$ 99.00
Cat# AP16195b
(40 western blots)
Availability: In Stock
Bulk Size
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