|Application ||WB, IF, E|
|Other Accession||Q01713, P79288, O35739, NP_001197.1|
|Predicted||Mouse, Rat, Pig|
|Calculated MW||27235 Da|
|Antigen Region||29-57 aa|
|Other Names||Krueppel-like factor 9, Basic transcription element-binding protein 1, BTE-binding protein 1, GC-box-binding protein 1, Transcription factor BTEB1, KLF9, BTEB, BTEB1|
|Target/Specificity||This KLF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human KLF9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLF9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box. Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation (PubMed:22711835).|
|Tissue Location||Epidermis (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription.
Du, H., et al. Biol. Reprod. 83(2):205-211(2010)
Pabona, J.M., et al. Endocrinology 151(7):3396-3406(2010)
Gamper, I., et al. Exp. Hematol. 37(5):539-548(2009)
Kang, L., et al. Pathol. Int. 58(6):334-338(2008)
Simmen, F.A., et al. Reprod. Biol. Endocrinol. 6, 41 (2008) :
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