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GTF3C2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GTF3C2 Antibody (N-term) AP16251A
    GTF3C2 Antibody (N-term) (Cat. #AP16251a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the GTF3C2 antibody detected the GTF3C2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8WUA4
Other Accession NP_001512.1, NP_001030598.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 100680 Da
Antigen Region 141-170 aa
Additional Information
Gene ID 2976
Other Names General transcription factor 3C polypeptide 2, TF3C-beta, Transcription factor IIIC 110 kDa subunit, TFIIIC 110 kDa subunit, TFIIIC110, Transcription factor IIIC subunit beta, GTF3C2, KIAA0011
Target/Specificity This GTF3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the N-terminal region of human GTF3C2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGTF3C2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTF3C2
Synonyms KIAA0011
Function Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.
Cellular Location Nucleus.
Citations (0)

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Background

GTF3C2 is required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.

References

Dumay-Odelot, H., et al. J. Biol. Chem. 282(23):17179-17189(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)

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$ 295.00
$ 99.00
Cat# AP16251A
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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