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GBX1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GBX1 Antibody (Center) AP16293c
    GBX1 Antibody (Center) (Cat. #AP16293c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GBX1 antibody detected the GBX1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q14549
Other Accession NP_001092304.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 118-147 aa
Additional Information
Other Names Homeobox protein GBX-1, Gastrulation and brain-specific homeobox protein 1, GBX1
Target/Specificity This GBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the Central region of human GBX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGBX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBX1
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108} EMBL; AC010973; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; L11239; AAA36002.1; -; Genomic_DNA CCDS; CCDS43682.1; - PIR; S32510; S32510 RefSeq; NP_001092304.1; NM_001098834.2 PDB; 2M34; NMR; -; A=256-325 PDB; 2ME0; NMR; -; A=256-325 PDB; 2ME6; NMR; -; A=256-325 PDB; 2N8G; NMR; -; A=256-325 PDBsum; 2M34; - PDBsum; 2ME0; - PDBsum; 2ME6; - PDBsum; 2N8G; - ProteinModelPortal; Q14549; - SMR; Q14549; - BioGrid; 108906; 1 STRING; 9606.ENSP00000297537; - iPTMnet; Q14549; - PhosphoSitePlus; Q14549; - DMDM; 115502392; - EPD; Q14549; - MaxQB; Q14549; - PaxDb; Q14549; - PeptideAtlas; Q14549; - PRIDE; Q14549; - ProteomicsDB; 60040; - DNASU; 2636; - Ensembl; ENST00000297537; ENSP00000297537; ENSG00000164900 GeneID; 2636; - KEGG; hsa:2636; - UCSC; uc011kvg.3; human CTD; 2636; - DisGeNET; 2636; - EuPathDB; HostDB:ENSG00000164900.4; - GeneCards; GBX1; - HGNC; HGNC:4185; GBX1 HPA; HPA055783; - MIM; 603354; gene neXtProt; NX_Q14549; - OpenTargets; ENSG00000164900; - PharmGKB; PA28599; - eggNOG; KOG0489; Eukaryota eggNOG; ENOG410ZTBY; LUCA GeneTree; ENSGT00910000144024; - HOGENOM; HOG000060099; - HOVERGEN; HBG003967; - InParanoid; Q14549; - KO; K09321; - OMA; RARSEPC; - OrthoDB; EOG091G0SCQ; - PhylomeDB; Q14549; - TreeFam; TF351530; - ChiTaRS; GBX1; human GenomeRNAi; 2636; - PRO; PR:Q14549; - Proteomes; UP000005640; Chromosome 7 Bgee; ENSG00000164900; - CleanEx; HS_GBX1; - Genevisible; Q14549; HS GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro GO; GO:0007628; P:adult walking behavior; IEA:Ensembl GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl GO; GO:0019230; P:proprioception; IEA:Ensembl GO; GO:0097374; P:sensory neuron axon guidance; IEA:Ensembl GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW CDD; cd00086; homeodomain; 1 InterPro; IPR031251; GBX-1 InterPro; IPR009057; Homeobox-like_sf InterPro; IPR017970; Homeobox_CS InterPro; IPR001356; Homeobox_dom InterPro; IPR020479; Homeobox_metazoa PANTHER; PTHR24334:SF2; PTHR24334:SF2; 1 Pfam; PF00046; Homeobox; 1 PRINTS; PR00024; HOMEOBOX SMART; SM00389; HOX; 1 SUPFAM; SSF46689; SSF46689; 1 PROSITE; PS00027; HOMEOBOX_1; 1 PROSITE; PS50071; HOMEOBOX_2; 1 1: Evidence at protein level; 3D-structure; Complete proteome; DNA-binding; Homeobox; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 363 Homeobox protein GBX-1 /FTId=PRO_0000048878 DNA_BIND 261 320 Homeobox. {ECO:0000255|PROSITE- ProRule:PRU00108} COMPBIAS 5 22 Gly-rich COMPBIAS 33 179 Pro-rich COMPBIAS 60 133 Ala-rich VARIANT 194 194 A -> T (in dbSNP:rs11975799) /FTId=VAR_049579 STRAND 264 268 {ECO:0000244|PDB:2M34} HELIX 270 282 {ECO:0000244|PDB:2M34} HELIX 288 297 {ECO:0000244|PDB:2M34} HELIX 302 320 {ECO:0000244|PDB:2M34} SEQUENCE 363 AA; 37629 MW; 738A37958DBD2E43 CRC64; MQRAGGGSAP GGNGGGGGGG PGTAFSIDSL IGPPPPRSGH LLYTGYPMFM PYRPLVLPQA LAPAPLPAGL PPLAPLASFA GRLTNTFCAG LGQAVPSMVA LTTALPSFAE PPDAFYGPQE LAAAAAAAAA TAARNNPEPG GRRPEGGLEA DELLPAREKV AEPPPPPPPH FSETFPSLPA EGKVYSSDEE KLEASAGDPA GSEQEEEGSG GDSEDDGFLD SSAGGPGALL GPKPKLKGSL GTGAEEGAPV TAGVTAPGGK SRRRRTAFTS EQLLELEKEF HCKKYLSLTE RSQIAHALKL SEVQVKIWFQ NRRAKWKRIK AGNVSSRSGE PVRNPKIVVP IPVHVNRFAV RSQHQQMEQG ARP
Research Areas
Citations (0)

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Background

Contains 1 homeobox DNA-binding domain.

References

Huntriss, J., et al. Mol. Hum. Reprod. 12(5):283-289(2006)
Matsui, T., et al. FEBS Lett. 336(1):107-110(1993)
Matsui, T., et al. FEBS Lett. 322(2):181-185(1993)

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$ 295.00
$ 99.00
Cat# AP16293c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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