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TMOD1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMOD1 Antibody (Center) AP16327c
    TMOD1 Antibody (Center) (Cat. #AP16327c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TMOD1 antibody detected the TMOD1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28289
Other Accession A0JNC0, NP_001159588.1, NP_003266.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40569 Da
Antigen Region 170-198 aa
Additional Information
Gene ID 7111
Other Names Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod, TMOD1, D9S57E, TMOD
Target/Specificity This TMOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human TMOD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMOD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMOD1
Synonyms D9S57E, TMOD
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Cellular Location Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).
Tissue Location Highly expressed in the erythrocyte, heart and skeletal muscle
Research Areas
Citations (0)

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TMOD1 is a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.


Olsen, J.V., et al. Cell 127(3):635-648(2006)
Kong, K.Y., et al. J. Biol. Chem. 281(14):9589-9599(2006)
Vera, C., et al. Arch. Biochem. Biophys. 444(2):130-138(2005)
Pawlak, G., et al. Int. J. Cancer 110(3):368-373(2004)
Rho, S.B., et al. FEBS Lett. 557 (1-3), 57-63 (2004) :

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$ 295.00
$ 99.00
Cat# AP16327c
(40 western blots)
Availability: In Stock
Bulk Size
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