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NAT5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P61599 |
| Other Accession | Q7ZXR3, P61600, Q2PFM2, Q58ED9, NP_852669.1, NP_852668.1, NP_057184.1 |
| Reactivity | Human |
| Predicted | Zebrafish, Monkey, Mouse, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20368 Da |
| Antigen Region | 127-155 aa |
| Gene ID | 51126 |
|---|---|
| Other Names | N-alpha-acetyltransferase 20, Methionine N-acetyltransferase, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB complex subunit NAT5, NatB catalytic subunit, NAA20, NAT5 |
| Target/Specificity | This NAT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the C-terminal region of human NAT5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NAT5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAA20 |
|---|---|
| Synonyms | NAT5 |
| Function | Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln (PubMed:34230638). Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration. |
| Cellular Location | Cytoplasm. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM].
References
Kuo, H.P., et al. Sci Signal 3 (108), RA9 (2010) :
Evjenth, R., et al. J. Biol. Chem. 284(45):31122-31129(2009)
Polevoda, B., et al. BMC Proc 3 SUPPL 6, S2 (2009) :
Starheim, K.K., et al. Biochem. J. 415(2):325-331(2008)
Sanchez-Puig, N., et al. Protein Sci. 15(8):1968-1976(2006)
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