|Application ||WB, E|
|Other Accession||Q7ZXR3, P61600, Q2PFM2, Q58ED9, NP_852669.1, NP_852668.1, NP_057184.1|
|Predicted||Zebrafish, Monkey, Mouse, Xenopus|
|Calculated MW||20368 Da|
|Antigen Region||127-155 aa|
|Other Names||N-alpha-acetyltransferase 20, Methionine N-acetyltransferase, N-acetyltransferase 5, N-terminal acetyltransferase B complex catalytic subunit NAA20, N-terminal acetyltransferase B complex catalytic subunit NAT5, NatB complex subunit NAT5, NatB catalytic subunit, NAA20, NAT5|
|Target/Specificity||This NAT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the C-terminal region of human NAT5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NAT5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.|
|Cellular Location||Cytoplasm. Nucleus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM].
Kuo, H.P., et al. Sci Signal 3 (108), RA9 (2010) :
Evjenth, R., et al. J. Biol. Chem. 284(45):31122-31129(2009)
Polevoda, B., et al. BMC Proc 3 SUPPL 6, S2 (2009) :
Starheim, K.K., et al. Biochem. J. 415(2):325-331(2008)
Sanchez-Puig, N., et al. Protein Sci. 15(8):1968-1976(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.