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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SSR4 Antibody (Center)   

SSR4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SSR4 Antibody (Center) AP16417C
    SSR4 Antibody (Center) (Cat. #AP16417c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SSR4 antibody detected the SSR4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51571
Other Accession NP_006271.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18999 Da
Antigen Region 98-126 aa
Additional Information
Gene ID 6748
Other Names Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta, SSR4, TRAPD
Target/Specificity This SSR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human SSR4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSR4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSR4
Synonyms TRAPD
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.


Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Wang, Z., et al. Melanoma Res. 14(2):107-114(2004)
Miyazaki, K., et al. J. Biol. Chem. 279(12):11327-11335(2004)
Wang, L., et al. FEBS Lett. 457(3):316-322(1999)
Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)

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$ 295.00
$ 99.00
Cat# AP16417C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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