|Application ||WB, E|
|Calculated MW||45873 Da|
|Antigen Region||108-137 aa|
|Other Names||Zygote arrest protein 1, Oocyte-specific maternal effect factor, ZAR1|
|Target/Specificity||This ZAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-137 amino acids from the Central region of human ZAR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZAR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential for female fertility. May play a role in the oocyte-to-embryo transition (By similarity).|
|Tissue Location||Ovary and testis.|
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Provided below are standard protocols that you may find useful for product applications.
The female gamete, the oocyte, serves the distinct purpose of transmitting the maternal genome and other maternal factors critical for postovulation events. Oocytes have diverse functions in ovarian folliculogenesis, fertilization, and embryogenesis. ZAR1 is an oocyte-specific gene that appears to function at the oocyte-to-gamete transition (Wu et al., 2003 [PubMed 12539046]).
Shinojima, Y., et al. J. Dermatol. Sci. 59(2):98-106(2010)
Uzbekova, S., et al. Reprod. Biol. Endocrinol. 4, 12 (2006) :
Wu, X., et al. Biol. Reprod. 69(3):861-867(2003)
Wu, X., et al. Nat. Genet. 33(2):187-191(2003)
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