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>   home   >   Products   >   Primary Antibodies   >   FOSL2 Antibody (C-term)   

FOSL2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FOSL2 Antibody (C-term) AP16490B
    FOSL2 Antibody (C-term) (Cat. #AP16490b) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the FOSL2 antibody detected the FOSL2 protein (arrow).
  • IF - FOSL2 Antibody (C-term) AP16490B
    Fluorescent confocal image of A549 cell stained with FOSL2 Antibody (C-term)(Cat#AP16490b).A549 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with FOSL2 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min). FOSL2 immunoreactivity is localized to Nucleus significantly.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15408
Other Accession NP_005244.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35193 Da
Antigen Region 220-248 aa
Additional Information
Gene ID 2355
Other Names Fos-related antigen 2, FRA-2, FOSL2, FRA2
Target/Specificity This FOSL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the C-terminal region of human FOSL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOSL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOSL2
Synonyms FRA2
Function Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.
Cellular Location Nucleus.
Citations (0)

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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.


Bozec, A., et al. J. Cell Biol. 190(6):1093-1106(2010)
Bolat, I., et al. Folia Histochem. Cytobiol. 48(2):197-201(2010)
Reich, N., et al. Arthritis Rheum. 62(1):280-290(2010)
Maurer, B., et al. Circulation 120(23):2367-2376(2009)
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :

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Cat# AP16490B
(40 western blots)
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