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ACCN4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ACCN4 Antibody (N-term) AP16518A
    ACCN4 Antibody (N-term) (Cat. #AP16518a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ACCN4 antibody detected the ACCN4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96FT7
Other Accession NP_061144.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70105 Da
Antigen Region 23-52 aa
Additional Information
Gene ID 55515
Other Names Acid-sensing ion channel 4, ASIC4, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, pituitary, ASIC4, ACCN4
Target/Specificity This ACCN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human ACCN4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACCN4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASIC4
Synonyms ACCN4
Function Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti
Research Areas
Citations (0)

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This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.


Donier, E., et al. Eur. J. Neurosci. 28(1):74-86(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Grunder, S., et al. Eur. J. Hum. Genet. 9(9):672-676(2001)
Grunder, S., et al. Neuroreport 11(8):1607-1611(2000)

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$ 295.00
$ 99.00
Cat# AP16518A
(40 western blots)
Availability: In Stock
Bulk Size
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