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ACCN4 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16518a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16518a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ACCN4 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q96FT7 |
| Other Accession | NP_061144.3 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 70105 Da |
ACCN4 Antibody (N-term) - Additional info | |
| Gene ID 55515 | |
| Other Names ASIC4; ACCN4; Acid-sensing ion channel 4; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4, pituitary | |
| Target/Specificity This ACCN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-52 amino acids from the N-terminal region of human ACCN4. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACCN4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACCN4 Antibody (N-term) - Protein Information | |
| Name ASIC4 | |
| Synonyms ACCN4 | |
| Function Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity | |
| Cellular Location Membrane; Multi-pass membrane protein (By similarity) | |
| Tissue Location Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti | |
ACCN4 Antibody (N-term) - Related products
ACCN4 Antibody (N-term) - Application data
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ACCN4 Antibody (N-term) (Cat. #AP16518a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ACCN4 antibody detected the ACCN4 protein (arrow).
ACCN4 Antibody (N-term) - Research Areas
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BACKGROUND
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
REFERENCES
Donier, E., et al. Eur. J. Neurosci. 28(1):74-86(2008) Lamesch, P., et al. Genomics 89(3):307-315(2007) Hillier, L.W., et al. Nature 434(7034):724-731(2005) Grunder, S., et al. Eur. J. Hum. Genet. 9(9):672-676(2001) Grunder, S., et al. Neuroreport 11(8):1607-1611(2000)
