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SYDE1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ZW31 |
| Other Accession | NP_149014.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 79793 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 85360 |
|---|---|
| Other Names | Rho GTPase-activating protein SYDE1, Synapse defective protein 1 homolog 1, Protein syd-1 homolog 1, SYDE1 |
| Target/Specificity | This SYDE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SYDE1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SYDE1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SYDE1 |
|---|---|
| Function | GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1 (PubMed:27917469). |
| Tissue Location | Expressed in trophoblast cells of placental villi. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity).
References
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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