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RIT2 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RIT2 Antibody (N-term) AP16551a
    RIT2 Antibody (N-term) (Cat. #AP16551a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RIT2 antibody detected the RIT2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99578
Other Accession Q5BJQ5, P70425, NP_002921.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 24668 Da
Antigen Region 41-69 aa
Additional Information
Gene ID 6014
Other Names GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2, RIT2, RIN, ROC2
Target/Specificity This RIT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-69 amino acids from the N-terminal region of human RIT2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRIT2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIT2
Synonyms RIN, ROC2
Function Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Cellular Location Nucleus. Cell membrane. Note=Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).
Tissue Location Neuron-specific.
Research Areas
Citations (0)
citation

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Background

RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM].

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010)
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :
Wu, C., et al. Proteomics 7(11):1775-1785(2007)

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$ 182.50
$ 70.00
Cat# AP16551a
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