SSC5D Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | A1L4H1 |
Other Accession | NP_001138422.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 165743 Da |
Antigen Region | 869-897 aa |
Gene ID | 284297 |
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Other Names | Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D, Soluble scavenger protein with 5 SRCR domains, SSc5D, SSC5D |
Target/Specificity | This SSC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 869-897 amino acids from the Central region of human SSC5D. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SSC5D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SSC5D |
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Function | Binds to extracellular matrix proteins. Binds to pathogen- associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity). |
Cellular Location | Secreted. Cytoplasm. |
Tissue Location | Highly expressed in monocytes/macrophages and T- lymphocytes. Highly expressed in placenta and spleen, and also detected at lower levels in colon, and more weakly in lung, heart and kidney |
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Provided below are standard protocols that you may find useful for product applications.
References
Goncalves, C.M., et al. Mol. Immunol. 46(13):2585-2596(2009)
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