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FHOD1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FHOD1 Antibody (C-term) AP16586b
    FHOD1 Antibody (C-term) (Cat. #AP16586b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FHOD1 antibody detected the FHOD1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y613
Other Accession NP_037373.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 126551 Da
Antigen Region 985-1013 aa
Additional Information
Gene ID 29109
Other Names FH1/FH2 domain-containing protein 1, Formin homolog overexpressed in spleen 1, FHOS, Formin homology 2 domain-containing protein 1, FHOD1, FHOS, FHOS1
Target/Specificity This FHOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 985-1013 amino acids from the C-terminal region of human FHOD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFHOD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FHOD1
Synonyms FHOS, FHOS1
Function Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic
Tissue Location Ubiquitous. Highly expressed in spleen.
Research Areas
Citations (0)

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This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. [provided by RefSeq].


Hannemann, S., et al. J. Biol. Chem. 283(41):27891-27903(2008)
Schulte, A., et al. Structure 16(9):1313-1323(2008)
Takeya, R., et al. EMBO J. 27(4):618-628(2008)
Schulte, A., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 (PT 10), 878-881 (2007) :
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

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$ 295.00
$ 99.00
Cat# AP16586b
(40 western blots)
Availability: In Stock
Bulk Size
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