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RHOF Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HBH0 |
| Other Accession | NP_061907.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23625 Da |
| Antigen Region | 178-206 aa |
| Gene ID | 54509 |
|---|---|
| Other Names | Rho-related GTP-binding protein RhoF, Rho family GTPase Rif, Rho in filopodia, RHOF, ARHF, RIF |
| Target/Specificity | This RHOF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the C-terminal region of human RHOF. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RHOF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHOF |
|---|---|
| Synonyms | ARHF, RIF |
| Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.
References
Fan, L., et al. J. Cell. Sci. 123 (PT 8), 1247-1252 (2010) :
Carbone, A., et al. Genes Chromosomes Cancer 47(12):1067-1075(2008)
Ellis, S., et al. Curr. Biol. 10(21):1387-1390(2000)
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