|Application ||WB, E|
|Other Accession||Q99MT7, NP_076404.3|
|Calculated MW||41436 Da|
|Antigen Region||329-357 aa|
|Other Names||G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95|
|Target/Specificity||This GPR87 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the C-terminal region of human GPR87.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR87 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.|
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Provided below are standard protocols that you may find useful for product applications.
G protein-coupled receptors play a role in cell communication. They are characterized by an extracellular N terminus, 7 transmembrane regions, and an intracellular C terminus.
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Zhang, Y., et al. Cancer Res. 69(15):6049-6056(2009)
Glatt, S., et al. Int. J. Cancer 122(9):2008-2016(2008)
Gugger, M., et al. Dis. Markers 24(1):41-50(2008)
Tabata, K., et al. Biochem. Biophys. Res. Commun. 363(3):861-866(2007)
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