|Application ||WB, E|
|Calculated MW||60131 Da|
|Antigen Region||507-533 aa|
|Other Names||Copine-3, Copine III, CPNE3, CPN3, KIAA0636|
|Target/Specificity||This CPNE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-533 amino acids from the C-terminal region of human CPNE3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPNE3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands.
Heinrich, C., et al. Oncogene 29(11):1598-1610(2010)
Thomas, G., et al. Nat. Genet. 40(3):310-315(2008)
Cowland, J.B., et al. J. Leukoc. Biol. 74(3):379-388(2003)
Caudell, E.G., et al. Biochemistry 39(42):13034-13043(2000)
Creutz, C.E., et al. J. Biol. Chem. 273(3):1393-1402(1998)
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