|Application ||WB, E|
|Calculated MW||48283 Da|
|Antigen Region||252-281 aa|
|Other Names||Tektin-1, TEKT1|
|Target/Specificity||This TEKT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human TEKT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TEKT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme|
|Tissue Location||Predominantly expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.
Newby, P.R., et al. Eur. J. Hum. Genet. 18(9):1021-1026(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Iguchi, N., et al. Mol. Hum. Reprod. 8(6):525-530(2002)
Xu, M., et al. Int. J. Biochem. Cell Biol. 33(12):1172-1182(2001)
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