|Application ||WB, E|
|Calculated MW||19080 Da|
|Antigen Region||111-140 aa|
|Other Names||Epididymal-specific lipocalin-8, LCN8, LCN5|
|Target/Specificity||This LCN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human LCN8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LCN8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.|
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Provided below are standard protocols that you may find useful for product applications.
Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).
Suzuki, K., et al. Gene 339, 49-59 (2004) :
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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