GPX8 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8TED1 |
Other Accession | NP_001008398.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 23881 Da |
Antigen Region | 164-193 aa |
Gene ID | 493869 |
---|---|
Other Names | Probable glutathione peroxidase 8, GPx-8, GSHPx-8, GPX8 |
Target/Specificity | This GPX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human GPX8. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GPX8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPX8 |
---|---|
Cellular Location | Membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
GPX8 belongs to the glutathione peroxidase family. Glutathione peroxidase is an enzyme whose principal function is to protect against damage from endogenously-formed hydroxyperoxides, catalysing the reduction of hydroxyperoxides by glutathione. Several forms of the enzyme are known. It has a catalytic activity of 2 glutathione + H2O2 = glutathione disulfide + 2 H2O.
References
Toppo, S., et al. Antioxid. Redox Signal. 10(9):1501-1514(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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